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Concurrent BMP7 and FGF9 signalling governs AP-1 function to promote self-renewal of nephron progenitor cells

Self-renewal of nephron progenitor cells (NPCs) is governed by BMP, FGF and WNT signalling. Mechanisms underlying cross-talk between these pathways at the molecular level are largely unknown. Here we delineate the pathway through which the proliferative BMP7 signal is transduced in NPCs in the mouse...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Muthukrishnan, Sree Deepthi, Yang, Xuehui, Friesel, Robert, Oxburgh, Leif
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686668/
https://ncbi.nlm.nih.gov/pubmed/26634297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10027
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