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Parameterization and Analysis of Peptide-Based Catalysts for the Atroposelective Bromination of 3-Arylquinazolin-4(3H)-ones

We report the development of a method to parameterize and predict the performance of structurally flexible β-turn-containing peptide catalysts, using the atroposelective bromination of 3-arylquinazolin-4(3H)-ones as a case study. The multivariate correlations obtained for tetrapeptides of two β-turn...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Crawford, Jennifer M., Stone, Elizabeth A., Metrano, Anthony J., Miller, Scott J., Sigman, Matthew S.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817992/
https://ncbi.nlm.nih.gov/pubmed/29300461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11303
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