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Molecular Dynamics Simulations of a Conformationally Mobile Peptide-Based Catalyst for Atroposelective Bromination

It is widely accepted that structural rigidity is required to achieve high levels of asymmetric induction in catalytic, enantioselective reactions. This fundamental design principle often does not apply to highly selective catalytic peptides that often exhibit conformational heterogeneity. As a resu...

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Dades bibliogràfiques
Publicat a:ACS Catal
Autors principals: Yan, Xin Cindy, Metrano, Anthony J., Robertson, Michael J., Abascal, Nadia C., Tirado–Rives, Julian, Miller, Scott J., Jorgensen, William L.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342276/
https://ncbi.nlm.nih.gov/pubmed/30687577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.8b03563
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