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Experimental Evolution of Diverse Strains as a Method for the Determination of Biochemical Mechanisms of Action for Novel Pyrrolizidinone Antibiotics

The continuing rise of multidrug resistant pathogens has made it clear that in the absence of new antibiotics we are moving toward a “postantibiotic” world, in which even routine infections will become increasingly untreatable. There is a clear need for the development of new antibiotics with truly...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Beabout, Kathryn, McCurry, Megan D., Mehta, Heer, Shah, Akshay A., Pulukuri, Kiran Kumar, Rigol, Stephan, Wang, Yanping, Nicolaou, K. C., Shamoo, Yousif
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817888/
https://ncbi.nlm.nih.gov/pubmed/28942642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.7b00135
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