Investigation of antitumor activities of trastuzumab delivered by PLGA nanoparticles

BACKGROUND: We report the development of an efficient antibody delivery system for the incorporation of trastuzumab (TZ) into poly(lactic-co-glycolic) acid nanoparticles (PLGA NPs). The aim of the work was to overcome the current limitations in the clinical use of therapeutic antibodies, including i...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Colzani, Barbara, Pandolfi, Laura, Hoti, Ada, Iovene, Pietro Alessandro, Natalello, Antonino, Avvakumova, Svetlana, Colombo, Miriam, Prosperi, Davide
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2018
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817418/
https://ncbi.nlm.nih.gov/pubmed/29491709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S152742
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