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Multivalent exposure of trastuzumab on iron oxide nanoparticles improves antitumor potential and reduces resistance in HER2-positive breast cancer cells

Targeted therapies have profoundly changed the clinical prospect in human epidermal growth factor receptor 2 (HER2)-positive breast cancer. In particular, the anti-HER2 monoclonal antibody trastuzumab represents the gold standard for the treatment of HER2+ breast cancer patients. Its contribution in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Truffi, Marta, Colombo, Miriam, Sorrentino, Luca, Pandolfi, Laura, Mazzucchelli, Serena, Pappalardo, Francesco, Pacini, Chiara, Allevi, Raffaele, Bonizzi, Arianna, Corsi, Fabio, Prosperi, Davide
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920071/
https://ncbi.nlm.nih.gov/pubmed/29700387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24968-x
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