Association of CTH variant with sinusoidal obstruction syndrome in children receiving intravenous busulfan and cyclophosphamide before hematopoietic stem cell transplantation

Sinusoidal obstruction syndrome (SOS) is a severe complication of hematopoietic stem cell transplantation (HSCT) that can be fatal, often attributed to the conditioning regimen prior to HSCT. We evaluated the association of SOS risk with gene variants in cystathionase (CTH), an enzyme involved in gl...

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Dades bibliogràfiques
Publicat a:Pharmacogenomics J
Autors principals: Huezo-Diaz Curtis, P, Uppugunduri, C R S, Muthukumaran, J, Rezgui, M A, Peters, C, Bader, P, Duval, M, Bittencourt, H, Krajinovic, Maja, Ansari, Marc
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2018
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817388/
https://ncbi.nlm.nih.gov/pubmed/27779248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2016.65
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