GSTA1 diplotypes affect busulfan clearance and toxicity in children undergoing allogeneic hematopoietic stem cell transplantation: a multicenter study

Busulfan (BU) dose adjustment following therapeutic drug monitoring contributes to better outcome of hematopoietic stem cell transplantation (HSCT). Further improvement could be achieved through genotype-guided BU dose adjustments. To investigate this aspect, polymorphism within glutathione S transf...

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Publicat a:Oncotarget
Autors principals: Ansari, Marc, Curtis, Patricia Huezo-Diaz, Uppugunduri, Chakradhara Rao S., Rezgui, Mohammed Aziz, Nava, Tiago, Mlakar, Vid, Lesne, Laurence, Théoret, Yves, Chalandon, Yves, Dupuis, Lee L., Schechter, Tao, Bartelink, Imke H., Boelens, Jaap J., Bredius, Robbert, Dalle, Jean-Hugues, Azarnoush, Saba, Sedlacek, Petr, Lewis, Victor, Champagne, Martin, Peters, Christina, Bittencourt, Henrique, Krajinovic, Maja
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710889/
https://ncbi.nlm.nih.gov/pubmed/29207608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20310
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