GSTA1 diplotypes affect busulfan clearance and toxicity in children undergoing allogeneic hematopoietic stem cell transplantation: a multicenter study

Busulfan (BU) dose adjustment following therapeutic drug monitoring contributes to better outcome of hematopoietic stem cell transplantation (HSCT). Further improvement could be achieved through genotype-guided BU dose adjustments. To investigate this aspect, polymorphism within glutathione S transf...

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Publicado en:Oncotarget
Main Authors: Ansari, Marc, Curtis, Patricia Huezo-Diaz, Uppugunduri, Chakradhara Rao S., Rezgui, Mohammed Aziz, Nava, Tiago, Mlakar, Vid, Lesne, Laurence, Théoret, Yves, Chalandon, Yves, Dupuis, Lee L., Schechter, Tao, Bartelink, Imke H., Boelens, Jaap J., Bredius, Robbert, Dalle, Jean-Hugues, Azarnoush, Saba, Sedlacek, Petr, Lewis, Victor, Champagne, Martin, Peters, Christina, Bittencourt, Henrique, Krajinovic, Maja
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710889/
https://ncbi.nlm.nih.gov/pubmed/29207608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20310
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