Direct Reprogramming of Spiral Ganglion Non-neuronal Cells into Neurons: Toward Ameliorating Sensorineural Hearing Loss by Gene Therapy

Primary auditory neurons (PANs) play a critical role in hearing by transmitting sound information from the inner ear to the brain. Their progressive degeneration is associated with excessive noise, disease and aging. The loss of PANs leads to permanent hearing impairment since they are incapable of...

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Bibliografski detalji
Izdano u:Front Cell Dev Biol
Glavni autori: Noda, Teppei, Meas, Steven J., Nogami, Jumpei, Amemiya, Yutaka, Uchi, Ryutaro, Ohkawa, Yasuyuki, Nishimura, Koji, Dabdoub, Alain
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Cell and Developmental Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817057/
https://ncbi.nlm.nih.gov/pubmed/29492404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00016
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