Direct Reprogramming of Spiral Ganglion Non-neuronal Cells into Neurons: Toward Ameliorating Sensorineural Hearing Loss by Gene Therapy

Primary auditory neurons (PANs) play a critical role in hearing by transmitting sound information from the inner ear to the brain. Their progressive degeneration is associated with excessive noise, disease and aging. The loss of PANs leads to permanent hearing impairment since they are incapable of...

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Bibliografiset tiedot
Julkaisussa:Front Cell Dev Biol
Päätekijät: Noda, Teppei, Meas, Steven J., Nogami, Jumpei, Amemiya, Yutaka, Uchi, Ryutaro, Ohkawa, Yasuyuki, Nishimura, Koji, Dabdoub, Alain
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Cell and Developmental Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817057/
https://ncbi.nlm.nih.gov/pubmed/29492404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00016
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