Direct Reprogramming of Spiral Ganglion Non-neuronal Cells into Neurons: Toward Ameliorating Sensorineural Hearing Loss by Gene Therapy

Primary auditory neurons (PANs) play a critical role in hearing by transmitting sound information from the inner ear to the brain. Their progressive degeneration is associated with excessive noise, disease and aging. The loss of PANs leads to permanent hearing impairment since they are incapable of...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Cell Dev Biol
Main Authors: Noda, Teppei, Meas, Steven J., Nogami, Jumpei, Amemiya, Yutaka, Uchi, Ryutaro, Ohkawa, Yasuyuki, Nishimura, Koji, Dabdoub, Alain
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2018
נושאים:
Cell and Developmental Biology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817057/
https://ncbi.nlm.nih.gov/pubmed/29492404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2018.00016
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