p66Shc Signaling Mediates Diabetes-Related Cognitive Decline

Accumlating evidence have suggested that diabetes mellitus links dementia, notably of Alzheimer’s disease (AD). However, the underlying mechanism remains unclear. Several studies have shown oxidative stress (OS) to be one of the major factors in the pathogenesis of diabetic complications. Here we sh...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Minami, Yohei, Sonoda, Noriyuki, Hayashida, Eiichi, Makimura, Hiroaki, Ide, Makoto, Ikeda, Noriko, Ohgidani, Masahiro, Kato, Takahiro A., Seki, Yoshihiro, Maeda, Yasutaka, Kanba, Shigenobu, Takayanagi, Ryoichi, Ogawa, Yoshihiro, Inoguchi, Toyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816624/
https://ncbi.nlm.nih.gov/pubmed/29453337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21426-6
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