The dipeptidyl peptidase-4 inhibitor, linagliptin, improves cognitive impairment in streptozotocin-induced diabetic mice by inhibiting oxidative stress and microglial activation

OBJECTIVE: Accumulating epidemiological studies have demonstrated that diabetes is an important risk factor for dementia. However, the underlying pathological and molecular mechanisms, and effective treatment, have not been fully elucidated. Herein, we investigated the effect of the dipeptidyl pepti...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS One
المؤلفون الرئيسيون: Ide, Makoto, Sonoda, Noriyuki, Inoue, Tomoaki, Kimura, Shinichiro, Minami, Yohei, Makimura, Hiroaki, Hayashida, Eiichi, Hyodo, Fuminori, Yamato, Mayumi, Takayanagi, Ryoichi, Inoguchi, Toyoshi
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2020
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006898/
https://ncbi.nlm.nih.gov/pubmed/32032367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228750
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