Mutations in Homologous Recombination Genes and Outcomes in Ovarian Carcinoma Patients in GOG 218: an NRG Oncology/Gynecologic Oncology Group Study

PURPOSE: We hypothesized that mutations in homologous recombination repair (HRR) genes beyond BRCA1 and BRCA2 improve outcomes for ovarian carcinoma (OC) patients treated with platinum therapy and would impact the relative benefit of adding prolonged bevacizumab. EXPERIMENTAL DESIGN: We sequenced DN...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Norquist, Barbara M., Brady, Mark F., Harrell, Maria I., Walsh, Tom, Lee, Ming K., Gulsuner, Suleyman, Bernards, Sarah S., Casadei, Silvia, Burger, Robert A., Tewari, Krishnansu S., Backes, Floor, Mannel, Robert S., Glaser, Gretchen, Bailey, Cheryl, Rubin, Stephen, Soper, John, Lankes, Heather A., Ramirez, Nilsa C., King, Mary Claire, Birrer, Michael J., Swisher, Elizabeth M.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815909/
https://ncbi.nlm.nih.gov/pubmed/29191972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1327
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker