Matrix Degradation in Human Immunodeficiency Virus Type 1–Associated Tuberculosis and Tuberculosis Immune Reconstitution Inflammatory Syndrome: A Prospective Observational Study

BACKGROUND: Extensive immunopathology occurs in human immunodeficiency virus (HIV)/tuberculosis (TB) coinfection, but the underlying molecular mechanisms are not well-defined. Excessive matrix metalloproteinase (MMP) activity is emerging as a key process but has not been systematically studied in HI...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Walker, Naomi F, Wilkinson, Katalin A, Meintjes, Graeme, Tezera, Liku B, Goliath, Rene, Peyper, Janique M, Tadokera, Rebecca, Opondo, Charles, Coussens, Anna K, Wilkinson, Robert J, Friedland, Jon S, Elkington, Paul T
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Articles and Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815569/
https://ncbi.nlm.nih.gov/pubmed/28475709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cix231
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