Procollagen III N-terminal Propeptide and Desmosine are Released by Matrix Destruction in Pulmonary Tuberculosis

Background. Tuberculosis is transmitted by patients with pulmonary disease. Matrix metalloproteinases (MMPs) drive lung destruction in tuberculosis but the resulting matrix degradation products (MDPs) have not been studied. We investigate the hypothesis that MMP activity generates matrix turnover pr...

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Detalhes bibliográficos
Main Authors: Seddon, Jo, Kasprowicz, Victoria, Walker, Naomi F., Yuen, Ho Ming, Sunpath, Henry, Tezera, Liku, Meintjes, Graeme, Wilkinson, Robert J., Bishai, William R., Friedland, Jon S., Elkington, Paul T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805234/
https://ncbi.nlm.nih.gov/pubmed/23922364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit343
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