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Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I mediated immunity

The sensor retinoic acid-inducible gene-I (RIG-I) detects double-stranded RNA derived from RNA viruses. Although RIG-I is also known to play a role in the antiviral response to DNA viruses, physiological RNA species recognized by RIG-I during DNA virus infection are largely unknown. Using next-gener...

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Vydáno v:Nat Immunol
Hlavní autoři: Chiang, Jessica J., Sparrer, Konstantin M.J., van Gent, Michiel, Lässig, Charlotte, Huang, Teng, Osterrieder, Nikolaus, Hopfner, Karl-Peter, Gack, Michaela U.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815369/
https://ncbi.nlm.nih.gov/pubmed/29180807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-017-0005-y
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