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Jointly aligning a group of DNA reads improves accuracy of identifying large deletions
Performing sequence alignment to identify structural variants, such as large deletions, from genome sequencing data is a fundamental task, but current methods are far from perfect. The current practice is to independently align each DNA read to a reference genome. We show that the propensity of geno...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5815140/ https://ncbi.nlm.nih.gov/pubmed/29182778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1175 |
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