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A mostly traditional approach improves alignment of bisulfite-converted DNA
Cytosines in genomic DNA are sometimes methylated. This affects many biological processes and diseases. The standard way of measuring methylation is to use bisulfite, which converts unmethylated cytosines to thymines, then sequence the DNA and compare it to a reference genome sequence. We describe a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401460/ https://ncbi.nlm.nih.gov/pubmed/22457070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks275 |
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