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Incorporating sequence quality data into alignment improves DNA read mapping
New DNA sequencing technologies have achieved breakthroughs in throughput, at the expense of higher error rates. The primary way of interpreting biological sequences is via alignment, but standard alignment methods assume the sequences are accurate. Here, we describe how to incorporate the per-base...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853142/ https://ncbi.nlm.nih.gov/pubmed/20110255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq010 |
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