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Incorporating sequence quality data into alignment improves DNA read mapping
New DNA sequencing technologies have achieved breakthroughs in throughput, at the expense of higher error rates. The primary way of interpreting biological sequences is via alignment, but standard alignment methods assume the sequences are accurate. Here, we describe how to incorporate the per-base...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853142/ https://ncbi.nlm.nih.gov/pubmed/20110255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq010 |
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