FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells

Common Chromosomal Fragile Sites (CFSs) are specific genomic regions prone to form breaks on metaphase chromosomes in response to replication stress. Moreover, CFSs are mutational hotspots in cancer genomes, showing that the mutational mechanisms that operate at CFSs are highly active in cancer cell...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Pentzold, Constanze, Shah, Shiraz Ali, Hansen, Niels Richard, Le Tallec, Benoît, Seguin-Orlando, Andaine, Debatisse, Michelle, Lisby, Michael, Oestergaard, Vibe H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2018
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815096/
https://ncbi.nlm.nih.gov/pubmed/29253234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1260
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