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FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells
Common Chromosomal Fragile Sites (CFSs) are specific genomic regions prone to form breaks on metaphase chromosomes in response to replication stress. Moreover, CFSs are mutational hotspots in cancer genomes, showing that the mutational mechanisms that operate at CFSs are highly active in cancer cell...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5815096/ https://ncbi.nlm.nih.gov/pubmed/29253234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1260 |
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