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Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy
Labeling of long RNA molecules in a site-specific yet generally applicable manner is integral to many spectroscopic applications. Here we present a novel covalent labeling approach that is site-specific and scalable to long intricately folded RNAs. In this approach, a custom-designed DNA strand that...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5814972/ https://ncbi.nlm.nih.gov/pubmed/29136199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1100 |
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