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Nucleophilic Water Capture or Proton Loss: Single Amino Acid Switch Converts δ‐Cadinene Synthase into Germacradien‐4‐ol Synthase
δ‐Cadinene synthase is a sesquiterpene cyclase that utilises the universal achiral precursor farnesyl diphosphate (FDP) to generate predominantly the bicyclic sesquiterpene δ‐cadinene and about 2 % germacradien‐4‐ol, which is also generated from FDP by the cyclase germacradien‐4‐ol synthase. Herein,...
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Gepubliceerd in: | Chembiochem |
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Hoofdauteurs: | , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
John Wiley and Sons Inc.
2017
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5814876/ https://ncbi.nlm.nih.gov/pubmed/29115742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700531 |
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