Mechanism of Germacradien-4-ol Synthase-Controlled Water Capture

[Image: see text] The sesquiterpene synthase germacradiene-4-ol synthase (GdolS) from Streptomyces citricolor is one of only a few known high-fidelity terpene synthases that convert farnesyl diphosphate (FDP) into a single hydroxylated product. Crystals of unliganded GdolS-E248A diffracted to 1.50 Å...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Grundy, Daniel J., Chen, Mengbin, González, Verónica, Leoni, Stefano, Miller, David J., Christianson, David W., Allemann, Rudolf K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829482/
https://ncbi.nlm.nih.gov/pubmed/26998816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00115
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