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Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse

There is no therapeutic intervention proven to prevent acute respiratory distress syndrome (ARDS). Novel mechanistic insights into the pathophysiology of ARDS are therefore required. Platelets are implicated in regulating many of the pathogenic processes that occur during ARDS; however, the mechanis...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Lax, Siân, Rayes, Julie, Wichaiyo, Surasak, Haining, Elizabeth J., Lowe, Kate, Grygielska, Beata, Laloo, Ryan, Flodby, Per, Borok, Zea, Crandall, Edward D., Thickett, David R., Watson, Steve P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814702/
https://ncbi.nlm.nih.gov/pubmed/28839100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00023.2017
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