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Differential localization and anabolic responsiveness of mTOR complexes in human skeletal muscle in response to feeding and exercise

Mechanistic target of rapamycin (mTOR) resides as two complexes within skeletal muscle. mTOR complex 1 [mTORC1–regulatory associated protein of mTOR (Raptor) positive] regulates skeletal muscle growth, whereas mTORC2 [rapamycin-insensitive companion of mTOR (Rictor) positive] regulates insulin sensi...

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Podrobná bibliografie
Vydáno v:Am J Physiol Cell Physiol
Hlavní autoři: Hodson, Nathan, McGlory, Chris, Oikawa, Sara Y., Jeromson, Stewart, Song, Zhe, Rüegg, Markus A., Hamilton, D. Lee, Phillips, Stuart M., Philp, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814591/
https://ncbi.nlm.nih.gov/pubmed/28971834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00176.2017
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