Differential localization and anabolic responsiveness of mTOR complexes in human skeletal muscle in response to feeding and exercise

Mechanistic target of rapamycin (mTOR) resides as two complexes within skeletal muscle. mTOR complex 1 [mTORC1–regulatory associated protein of mTOR (Raptor) positive] regulates skeletal muscle growth, whereas mTORC2 [rapamycin-insensitive companion of mTOR (Rictor) positive] regulates insulin sensi...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Cell Physiol
Main Authors: Hodson, Nathan, McGlory, Chris, Oikawa, Sara Y., Jeromson, Stewart, Song, Zhe, Rüegg, Markus A., Hamilton, D. Lee, Phillips, Stuart M., Philp, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2017
Fag:
Rapid Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814591/
https://ncbi.nlm.nih.gov/pubmed/28971834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00176.2017
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