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Differential localization and anabolic responsiveness of mTOR complexes in human skeletal muscle in response to feeding and exercise

Mechanistic target of rapamycin (mTOR) resides as two complexes within skeletal muscle. mTOR complex 1 [mTORC1–regulatory associated protein of mTOR (Raptor) positive] regulates skeletal muscle growth, whereas mTORC2 [rapamycin-insensitive companion of mTOR (Rictor) positive] regulates insulin sensi...

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Publicat a:Am J Physiol Cell Physiol
Autors principals: Hodson, Nathan, McGlory, Chris, Oikawa, Sara Y., Jeromson, Stewart, Song, Zhe, Rüegg, Markus A., Hamilton, D. Lee, Phillips, Stuart M., Philp, Andrew
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814591/
https://ncbi.nlm.nih.gov/pubmed/28971834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00176.2017
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