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Differential localization and anabolic responsiveness of mTOR complexes in human skeletal muscle in response to feeding and exercise

Mechanistic target of rapamycin (mTOR) resides as two complexes within skeletal muscle. mTOR complex 1 [mTORC1–regulatory associated protein of mTOR (Raptor) positive] regulates skeletal muscle growth, whereas mTORC2 [rapamycin-insensitive companion of mTOR (Rictor) positive] regulates insulin sensi...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Hodson, Nathan, McGlory, Chris, Oikawa, Sara Y., Jeromson, Stewart, Song, Zhe, Rüegg, Markus A., Hamilton, D. Lee, Phillips, Stuart M., Philp, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814591/
https://ncbi.nlm.nih.gov/pubmed/28971834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00176.2017
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