Development of an intradermal DNA vaccine delivery strategy to achieve single-dose immunity against respiratory syncytial virus

Respiratory syncytial virus (RSV) is a massive medical burden in infants, children and the elderly worldwide, and an effective, safe RSV vaccine remains an unmet need. Here we assess a novel vaccination strategy based on the intradermal delivery of a SynCon(®) DNA-based vaccine encoding engineered R...

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Publicado en:Vaccine
Main Authors: Smith, Trevor RF, Schultheis, Katherine, Morrow, Matthew P, Kraynyak, Kimberly A, McCoy, Jay R, Yim, Kevin C, Muthumani, Karuppiah, Humeau, Laurent, Weiner, David B, Sardesai, Niranjan Y, Broderick, Kate E
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814302/
https://ncbi.nlm.nih.gov/pubmed/28413132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.04.008
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