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Implications of KRAS mutations in acquired resistance to treatment in NSCLC
RATIONALE: KRAS is the most common and, simultaneously, the most ambiguous oncogene implicated in human cancer. Despite KRAS mutations were identified in Non Small Cell Lung Cancers (NSCLCs) more than 20 years ago, selective and specific inhibitors aimed at directly abrogating KRAS activity are not...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5814239/ https://ncbi.nlm.nih.gov/pubmed/29464099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23553 |
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