T cell infiltration into Ewing sarcomas is associated with local expression of immune-inhibitory HLA-G

Ewing sarcoma (EwS) is an aggressive mesenchymal cancer of bones or soft tissues. The mechanisms by which this cancer interacts with the host immune system to induce tolerance are not well understood. We hypothesized that the non-classical, immune-inhibitory HLA-molecule HLA-G contributes to immune...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Spurny, Christian, Kailayangiri, Sareetha, Altvater, Bianca, Jamitzky, Silke, Hartmann, Wolfgang, Wardelmann, Eva, Ranft, Andreas, Dirksen, Uta, Amler, Susanne, Hardes, Jendrik, Fluegge, Maike, Meltzer, Jutta, Farwick, Nicole, Greune, Lea, Rossig, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814230/
https://ncbi.nlm.nih.gov/pubmed/29464090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23815
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