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Carbohydrate Targets for CAR T Cells in Solid Childhood Cancers
Application of the CAR targeting strategy in solid tumors is challenged by the need for adequate target antigens. As a consequence of their tissue origin, embryonal cancers can aberrantly express membrane-anchored gangliosides. These are carbohydrate molecules consisting of a glycosphingolipid linke...
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| Pubblicato in: | Front Oncol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6240699/ https://ncbi.nlm.nih.gov/pubmed/30483473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00513 |
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