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Combination of a thioxodihydroquinazolinone with cisplatin eliminates ovarian cancer stem cell-like cells (CSC-LCs) and shows preclinical potential

Cancer stem cell-like cells (CSC-LCs) contribute to drug resistance and recurrence of ovarian cancer. Strategies that can eradicate CSC-LCs are expected to substantially improve the outcome of ovarian cancer treatment. We have previously identified a class of thioxodihydroquinazolinone small molecul...

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Publicat a:Oncotarget
Autors principals: Ma, Jing, Salamoun, Joseph, Wipf, Peter, Edwards, Robert, Van Houten, Bennett, Qian, Wei
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814193/
https://ncbi.nlm.nih.gov/pubmed/29464053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23679
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