Cyclin-dependent kinase inhibitor dinaciclib potently synergizes with cisplatin in preclinical models of ovarian cancer

Ovarian cancer is one of the most lethal of woman cancers, and its clinical therapeutic outcome currently is unsatisfied. Dinaciclib, a novel small molecule inhibitor of CDK1, CDK2, CDK5 and CDK9, is assessed in clinical trials for the treatment of several types of cancers. In this study, we investi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Xiu-Xiu, Xie, Feng-Feng, Zhu, Xiu-Jie, Lin, Feng, Pan, Shi-Shi, Gong, Li-Hua, Qiu, Jian-Ge, Zhang, Wen-Ji, Jiang, Qi-Wei, Mei, Xiao-Long, Xue, You-Qiu, Qin, Wu-Ming, Shi, Zhi, Yan, Xiao-Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558126/
https://ncbi.nlm.nih.gov/pubmed/25962959
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