Two-mAb Cocktail Protects Macaques Against The Makona Variant of Ebola Virus

The 2014–15 Ebola virus (EBOV) outbreak in West Africa highlighted the urgent need for specific therapeutic interventions for infected patients. The human-mouse chimeric monoclonal antibody (mAb) cocktail ZMapp(™), previously shown to be efficacious in EBOV (variant Kikwit) lethally infected nonhuma...

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Veröffentlicht in:Sci Transl Med
Hauptverfasser: Qiu, Xiangguo, Audet, Jonathan, Lv, Ming, He, Shihua, Wong, Gary, Wei, Haiyan, Luo, Longlong, Fernando, Lisa, Kroeker, Andrea, Bovendo, Hugues Fausther, Bello, Alexander, Li, Feng, Ye, Pei, Jacobs, Michael, Ippolito, Giuseppe, Saphire, Erica Ollmann, Bi, Shengli, Shen, Beifen, Gao, George F, Zeitlin, Larry, Feng, Jiannan, Zhang, Boyan, Kobinger, Gary P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814125/
https://ncbi.nlm.nih.gov/pubmed/26962157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad9875
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