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Pre-existing immunity against Ad vectors: Humoral, cellular, and innate response, what's important?
Pre-existing immunity against human adenovirus (HAd) serotype 5 derived vector in the human population is widespread, thus hampering its clinical use. Various components of the immune system, including neutralizing antibodies (nAbs), Ad specific T cells and type I IFN activated NK cells, contribute...
Gespeichert in:
| Veröffentlicht in: | Hum Vaccin Immunother |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5443060/ https://ncbi.nlm.nih.gov/pubmed/25483662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.29594 |
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