An Adenovirus Vaccine Expressing Ebola Virus Variant Makona Glycoprotein Is Efficacious in Guinea Pigs and Nonhuman Primates

A licensed vaccine against Ebola virus (EBOV) remains unavailable, despite >11 000 deaths from the 2014–2016 outbreak of EBOV disease in West Africa. Past studies have shown that recombinant vaccine viruses expressing EBOV glycoprotein (GP) are able to protect nonhuman primates (NHPs) from a leth...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Wu, Shipo, Kroeker, Andrea, Wong, Gary, He, Shihua, Hou, Lihua, Audet, Jonathan, Wei, Haiyan, Zhang, Zhe, Fernando, Lisa, Soule, Geoff, Tran, Kaylie, Bi, Shengli, Zhu, Tao, Yu, Xuefeng, Chen, Wei, Qiu, Xiangguo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Ebola Outbreak in West Africa
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050474/
https://ncbi.nlm.nih.gov/pubmed/27493239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw250
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