Adenovirus-Vectored Vaccine Provides Postexposure Protection to Ebola Virus–Infected Nonhuman Primates

Ebola virus (EBOV) causes lethal disease in up to 90% of EBOV-infected humans. Among vaccines, only the vesicular stomatitis virus platform has been successful in providing postexposure protection in nonhuman primates. Here, we show that an adjuvanted human adenovirus serotype 5 (Ad5)–vectored vacci...

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Библиографические подробности
Опубликовано в: :J Infect Dis
Главные авторы: Wong, Gary, Richardson, Jason S., Pillet, Stéphane, Racine, Trina, Patel, Ami, Soule, Geoff, Ennis, Jane, Turner, Jeffrey, Qiu, Xiangguo, Kobinger, Gary P.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564535/
https://ncbi.nlm.nih.gov/pubmed/25957963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv102
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