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An Adenovirus Vaccine Expressing Ebola Virus Variant Makona Glycoprotein Is Efficacious in Guinea Pigs and Nonhuman Primates

A licensed vaccine against Ebola virus (EBOV) remains unavailable, despite >11 000 deaths from the 2014–2016 outbreak of EBOV disease in West Africa. Past studies have shown that recombinant vaccine viruses expressing EBOV glycoprotein (GP) are able to protect nonhuman primates (NHPs) from a leth...

詳細記述

保存先:
書誌詳細
出版年:J Infect Dis
主要な著者: Wu, Shipo, Kroeker, Andrea, Wong, Gary, He, Shihua, Hou, Lihua, Audet, Jonathan, Wei, Haiyan, Zhang, Zhe, Fernando, Lisa, Soule, Geoff, Tran, Kaylie, Bi, Shengli, Zhu, Tao, Yu, Xuefeng, Chen, Wei, Qiu, Xiangguo
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050474/
https://ncbi.nlm.nih.gov/pubmed/27493239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw250
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