Kinetics of PTEN-mediated PI(3,4,5)P3 hydrolysis on solid supported membranes

Phosphatidylinositides play important roles in cellular signaling and migration. Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) is an important phosphatidylinositide because it acts as a secondary messenger to trigger cell movement and proliferation. A high level of PI(3,4,5)P3 at the plasma...

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Bibliographic Details
Published in:PLoS One
Main Authors: Liu, Chun, Deb, Sanghamitra, Ferreira, Vinicius S., Xu, Eric, Baumgart, Tobias
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813967/
https://ncbi.nlm.nih.gov/pubmed/29447222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192667
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