Tonic B-cell receptor signaling in diffuse large B-cell lymphoma

We used clustered regularly interspaced short palindromic repeats/Cas9-mediated genomic modification to investigate B-cell receptor (BCR) signaling in cell lines of diffuse large B-cell lymphoma (DLBCL). Three manipulations that altered BCR genes without affecting surface BCR levels showed that BCR...

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Vydáno v:Blood
Hlavní autoři: Havranek, Ondrej, Xu, Jingda, Köhrer, Stefan, Wang, Zhiqiang, Becker, Lisa, Comer, Justin M., Henderson, Jared, Ma, Wencai, Man Chun Ma, John, Westin, Jason R., Ghosh, Dipanjan, Shinners, Nicholas, Sun, Luhong, Yi, Allen F., Karri, Anusha R., Burger, Jan A., Zal, Tomasz, Davis, R. Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2017
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813722/
https://ncbi.nlm.nih.gov/pubmed/28646116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-747303
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