Targeting phosphatidylinositol 3 kinase-β and -δ for Bruton tyrosine kinase resistance in diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma; 40% of patients relapse after a complete response or are refractory to therapy. To survive, the activated B-cell (ABC) subtype of DLBCL relies upon B-cell receptor signaling, which can be modulated by the activ...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Jain, Neeraj, Singh, Satishkumar, Laliotis, Georgios, Hart, Amber, Muhowski, Elizabeth, Kupcova, Kristyna, Chrbolkova, Tereza, Khashab, Tamer, Chowdhury, Sayan Mullick, Sircar, Anuvrat, Shirazi, Fazal, Singh, Ram Kumar, Alinari, Lapo, Zhu, Jiangjiang, Havranek, Ondrej, Tsichlis, Philip, Woyach, Jennifer, Baiocchi, Robert, Samaniego, Felipe, Sehgal, Lalit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509871/
https://ncbi.nlm.nih.gov/pubmed/32926124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001685
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