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Advances in understanding tumour evolution through single-cell sequencing()

The mutational heterogeneity observed within tumours poses additional challenges to the development of effective cancer treatments. A thorough understanding of a tumour's subclonal composition and its mutational history is essential to open up the design of treatments tailored to individual pat...

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Foilsithe in:Biochim Biophys Acta Rev Cancer
Main Authors: Kuipers, Jack, Jahn, Katharina, Beerenwinkel, Niko
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813714/
https://ncbi.nlm.nih.gov/pubmed/28193548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2017.02.001
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