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Advances in understanding tumour evolution through single-cell sequencing()

The mutational heterogeneity observed within tumours poses additional challenges to the development of effective cancer treatments. A thorough understanding of a tumour's subclonal composition and its mutational history is essential to open up the design of treatments tailored to individual pat...

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Publicado en:Biochim Biophys Acta Rev Cancer
Autores principales: Kuipers, Jack, Jahn, Katharina, Beerenwinkel, Niko
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813714/
https://ncbi.nlm.nih.gov/pubmed/28193548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbcan.2017.02.001
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