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Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex

CD4(+) T cells convert the time that T cell receptors (TCRs) interact with peptides embedded within class II major histocompatibility complex molecules (pMHCII) into signals that direct cell-fate decisions. In principle, TCRs relay information to intracellular signaling motifs of the associated CD3...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Glassman, Caleb R., Parrish, Heather L., Lee, Mark S., Kuhns, Michael S.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813697/
https://ncbi.nlm.nih.gov/pubmed/29386113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.12.104
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