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3D Analysis of the TCR/pMHCII Complex Formation in Monkeys Vaccinated with the First Peptide Inducing Sterilizing Immunity against Human Malaria

T-cell receptor gene rearrangements were studied in Aotus monkeys developing high antibody titers and sterilizing immunity against the Plasmodium falciparum malaria parasite upon vaccination with the modified synthetic peptide 24112, which was identified in the Merozoite Surface Protein 2 (MSP-2) an...

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Bibliographische Detailangaben
Hauptverfasser: Patarroyo, Manuel A., Bermúdez, Adriana, López, Carolina, Yepes, Gloria, Patarroyo, Manuel E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841639/
https://ncbi.nlm.nih.gov/pubmed/20333301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009771
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