3D Analysis of the TCR/pMHCII Complex Formation in Monkeys Vaccinated with the First Peptide Inducing Sterilizing Immunity against Human Malaria

T-cell receptor gene rearrangements were studied in Aotus monkeys developing high antibody titers and sterilizing immunity against the Plasmodium falciparum malaria parasite upon vaccination with the modified synthetic peptide 24112, which was identified in the Merozoite Surface Protein 2 (MSP-2) an...

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Autors principals: Patarroyo, Manuel A., Bermúdez, Adriana, López, Carolina, Yepes, Gloria, Patarroyo, Manuel E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841639/
https://ncbi.nlm.nih.gov/pubmed/20333301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009771
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