Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition

Accurate predictions of T-cell epitopes would be useful for designing vaccines, immunotherapies for cancer and autoimmune diseases, and improved protein therapies. The humoral immune response involves uptake of antigens by antigen presenting cells (APCs), APC processing and presentation of peptides...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Schneidman-Duhovny, Dina, Khuri, Natalia, Dong, Guang Qiang, Winter, Michael B., Shifrut, Eric, Friedman, Nir, Craik, Charles S., Pratt, Kathleen P., Paz, Pedro, Aswad, Fred, Sali, Andrej
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219782/
https://ncbi.nlm.nih.gov/pubmed/30399156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206654
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