Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition

Accurate predictions of T-cell epitopes would be useful for designing vaccines, immunotherapies for cancer and autoimmune diseases, and improved protein therapies. The humoral immune response involves uptake of antigens by antigen presenting cells (APCs), APC processing and presentation of peptides...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Schneidman-Duhovny, Dina, Khuri, Natalia, Dong, Guang Qiang, Winter, Michael B., Shifrut, Eric, Friedman, Nir, Craik, Charles S., Pratt, Kathleen P., Paz, Pedro, Aswad, Fred, Sali, Andrej
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219782/
https://ncbi.nlm.nih.gov/pubmed/30399156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0206654
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